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A New Test for Cross‐Over Clinical Trials with Order Effects
Author(s) -
Le Chap T.
Publication year - 1984
Publication title -
biometrical journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.108
H-Index - 63
eISSN - 1521-4036
pISSN - 0323-3847
DOI - 10.1002/bimj.4710260516
Subject(s) - test (biology) , cross over , order (exchange) , binary number , statistics , computer science , mathematics , medicine , arithmetic , paleontology , finance , economics , biology
In cross‐over designs for the comparison of two treatments, A and B, each patient receives both treatments in a randomized order. We will consider such design when the response of each patient is binary and propose a new test for treatment effect incorporating the information available from like pairs of response.