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Power and Sample Size Calculation of Comparative Diagnostic Accuracy Studies with Multiple Correlated Test Results
Author(s) -
Liu Aiyi,
Schisterman Enrique F.,
Mazumdar Madhu,
Hu Jiang
Publication year - 2005
Publication title -
biometrical journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.108
H-Index - 63
eISSN - 1521-4036
pISSN - 0323-3847
DOI - 10.1002/bimj.200410094
Subject(s) - sample size determination , statistics , mathematics , power (physics) , statistical power , sample (material) , statistical hypothesis testing , diagnostic test , medicine , physics , emergency medicine , thermodynamics , quantum mechanics
We consider the power and sample size calculation of diagnostic studies with normally distributed multiple correlated test results. We derive test statistics and obtain power and sample size formulas. The methods are illustrated using an example of comparison of CT and PET scanner for detecting extra‐hepatic disease for colorectal cancer. (© 2005 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)