Premium
Multifunctional plasma membrane redox systems
Author(s) -
Medina Miguel Ángel,
CastilloOlivares Antonio Del,
De Castro Ignacio NúÑez
Publication year - 1997
Publication title -
bioessays
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.175
H-Index - 184
eISSN - 1521-1878
pISSN - 0265-9247
DOI - 10.1002/bies.950191107
Subject(s) - bioenergetics , redox , membrane , microbiology and biotechnology , function (biology) , signal transduction , reactive oxygen species , chemistry , cell , cell membrane , cell growth , cell function , biophysics , biology , biochemistry , mitochondrion , organic chemistry
Abstract All the biological membranes contain oxidoreduction systems actively involved in their bioenergetics. Plasma membrane redox systems seem to be ubiquitous and they have been related to several important functions, including not only their role in cell bioenergetics, but also in cell defense through the generation of reactive oxygen species, in iron uptake, in the control of cell growth and proliferation and in signal transduction. In the last few years, an increasing number of mechanistic and molecular studies have deeply widened our knowledge on the function of these plasma membrane redox systems. The aim of this review is to summarize what is currently known about the components and physiological roles of these systems.