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Myosin II function in non‐muscle cells
Author(s) -
Maciver Sutherland K.
Publication year - 1996
Publication title -
bioessays
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.175
H-Index - 184
eISSN - 1521-1878
pISSN - 0265-9247
DOI - 10.1002/bies.950180304
Subject(s) - cytokinesis , cleavage furrow , myosin , microbiology and biotechnology , mitosis , cell division , motility , biology , cleavage (geology) , aurora b kinase , cell , genetics , paleontology , fracture (geology)
Amongst the remarkable variety of motility that cells display, cytokinesis (cell division) is particularly striking. Dramatic changes in cell shape occur before, during and after cytokinesis. Myosin II is implicated in the ‘rounding up’ of cells prior to cytokinesis, and is essential in the formation of the contractile cleavage furrow during cytokinesis. Now it appears that myosin II plays a role in all stages of cytokinesis, as a recent report (1) suggests that myosin II drives post‐mitotic cell spreading. A similar type of motile mechanism operating in cell spreading may occur in other cell types in other situations.