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Molecular movements in oocyte patterning and pole cell differentiation
Author(s) -
Lasko Paul F.
Publication year - 1992
Publication title -
bioessays
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.175
H-Index - 184
eISSN - 1521-1878
pISSN - 0265-9247
DOI - 10.1002/bies.950140802
Subject(s) - oocyte , germ plasm , microbiology and biotechnology , biology , context (archaeology) , polarity in embryogenesis , germ cell , germ line development , cytoplasm , germline , embryonic stem cell , embryo , cellular differentiation , embryogenesis , genetics , gene , gastrulation , paleontology
Central to the differentiation and patterning of the Drosophila oocyte is the asymmetric intracellular localization of numerous mRNA and protein molecules involved in developmental signalling. Recent advances have identified some of the molecules mediating oocyte differentiation, specification of the anterior pole of the embryo, and determination of the embryonic germ line. This work is considered in the context of the classical model of the germ plasm as a cytoplasmic determinant for germ cell formation.