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Control of transcription of Drosophila retrotransposons
Author(s) -
Arkhipova Irina R.,
Ilyin Yurii V.
Publication year - 1992
Publication title -
bioessays
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.175
H-Index - 184
eISSN - 1521-1878
pISSN - 0265-9247
DOI - 10.1002/bies.950140305
Subject(s) - retrotransposon , biology , transcription (linguistics) , genetics , evolutionary biology , computational biology , gene , genome , philosophy , transposable element , linguistics
Studies of transcriptional control sequences responsible for regulated and basal‐level RNA synthesis from promoters of Drosophila melanogaster retrotransposons reveal novel aspects of gene regulation and lead to identification of trans ‐acting factors that can be involved in RNA polymerase II transcription not only of retrotransposons, but of many other cellular genes. Comparisons between promoters of retrotransposons and some other Drosophila genes demonstrate that there is a greater variety in basal promoter structure than previously thought and that many promoters may contain essential sequences downstream from the RNA start site.