Premium
Cellular and genetic responses to mesoderm induction in Xenopus
Author(s) -
Hopwood N. D.
Publication year - 1990
Publication title -
bioessays
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.175
H-Index - 184
eISSN - 1521-1878
pISSN - 0265-9247
DOI - 10.1002/bies.950121003
Subject(s) - mesoderm , xenopus , fgf and mesoderm formation , biology , nodal , microbiology and biotechnology , embryonic induction , paraxial mesoderm , lateral plate mesoderm , inducer , gastrulation , germ layer , genetics , embryo , embryogenesis , embryonic stem cell , gene , induced pluripotent stem cell
Mesodermal cell differentiation begins in response to an inductive interaction early in frog development. In parallel with the recent finding that certain peptide growth factors can induce mesoderm, early cellular and genetic responses to the induction have been discovered. I review here recent work on these responses, work that aims to understand how cells respond to inducers to form the complex pattern of the vertebrate mesoderm.