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Genetic control of cell communication in C. elegans development
Author(s) -
Maine Eleanor M.,
Kimble Judith
Publication year - 1990
Publication title -
bioessays
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.175
H-Index - 184
eISSN - 1521-1878
pISSN - 0265-9247
DOI - 10.1002/bies.950120604
Subject(s) - caenorhabditis elegans , biology , gene , genetic screen , genetics , cell , identification (biology) , computational biology , phenotype , ecology
Cell communication is crucial for many aspects of growth and differentiation during the development of the nematode Caenorhabditis elegans . Two genes, glp‐1 and lin‐12 , mediate a number of known cell–cell interactions. Genetic and molecular analyses of these two genes lead to the conclusion that they are structurally and functionally related. We summarize these studies as well as those involving the identification of other genes that interact with glp‐1 and / or lin‐12 .