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Glycoconjugate expression during embryogenesis and its biological significance
Author(s) -
Fenderson Bruce A.,
Eddy E. M.,
Hakomori SenItiroh
Publication year - 1990
Publication title -
bioessays
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.175
H-Index - 184
eISSN - 1521-1878
pISSN - 0265-9247
DOI - 10.1002/bies.950120406
Subject(s) - embryogenesis , biology , expression (computer science) , glycoconjugate , microbiology and biotechnology , evolutionary biology , computational biology , embryo , bioinformatics , computer science , programming language
Abstract Many stage‐specific embryonic antigens (SSEAs) have been identified as glycoconjugates. These molecules may play diverse roles in the development of the embryo, including regulation of cell growth, recognition, and differentiation. The example of SSEA‐1 is described in detail. This molecule appears to play an essential role in compaction of the early mouse embryo, and may illustrate the general importance of carbohydrate‐carbohydrate interactions in controlling cell surface interactions in development.