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Proto‐oncogenes in cell differentiation
Author(s) -
Zelenka Peggy S.
Publication year - 1990
Publication title -
bioessays
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.175
H-Index - 184
eISSN - 1521-1878
pISSN - 0265-9247
DOI - 10.1002/bies.950120105
Subject(s) - oncogene , biology , proto oncogenes , gene , oncogene proteins , cell , cellular differentiation , cell growth , microbiology and biotechnology , cell cycle , genetics , regulation of gene expression
Proto‐oncogene products may be multi‐functional proteins with various roles in cell differentiation as well as cell proliferation. The molecular biology of the gene products of three well characterized proto‐oncogenes ( c‐fos, c‐myc and c‐src ) are described, and the roles of three other proto‐oncogene products, involved in hormone and growth factor reception, are reviewed.