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The carbonic anhydrases: Widening perspectives on their evolution, expression and function
Author(s) -
Tashian Richard E.
Publication year - 1989
Publication title -
bioessays
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.175
H-Index - 184
eISSN - 1521-1878
pISSN - 0265-9247
DOI - 10.1002/bies.950100603
Subject(s) - carbonic anhydrase , isozyme , biology , function (biology) , gene , carbonic anhydrase ii , enzyme , biochemistry , genetics , microbiology and biotechnology , computational biology
Now, some 55 years after its discovery in bovine red cells, carbonic anhydrase (CA), in all its varied forms, continues to challenge and intrigue physiologists, biochemists and molecular geneticists. This is so because of an increasing awareness of the many apparently diverse functions of the different CA isozymes encoded by this large multigene family, the continuing discovery of new CA, or CA‐related, genes, and the extensive variation in their hormonal control, cellular expression and subcellular localization.