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The acetylcholine receptor: Its molecular biology and biotechnological prospects
Author(s) -
Changeux JeanPierre
Publication year - 1989
Publication title -
bioessays
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.175
H-Index - 184
eISSN - 1521-1878
pISSN - 0265-9247
DOI - 10.1002/bies.950100204
Subject(s) - acetylcholine receptor , allosteric regulation , acetylcholine , biology , receptor , computational biology , set (abstract data type) , microbiology and biotechnology , neuroscience , genetics , endocrinology , computer science , programming language
The structure and behaviour of the acetylcholine receptor (AChR) is described, and the evidence that it is an allosteric protein is discussed. The genes for the AChR subunits are subject to a complex set of spatio‐temporal transcriptional controls during development of the motor endplate, and these findings are reviewed here. Finally, the biotechnological prospects suggested by the new data are noted.