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Desmutagens and bio‐antimutagens – their modes of action
Author(s) -
Kada Tsuneo,
Shimoi Kayoko
Publication year - 1987
Publication title -
bioessays
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.175
H-Index - 184
eISSN - 1521-1878
pISSN - 0265-9247
DOI - 10.1002/bies.950070305
Subject(s) - mutagenesis , biology , genetics , dna , action (physics) , mutation , dna damage , dna repair , computational biology , gene , physics , quantum mechanics
There are two ways of preventing induced cellular mutagenesis. In the first, mutagens are inactivated by ‘desmutagens’ before they can attack the DNA. In the second, ‘bio‐antimutagens’ interfere with cellular fixation processes working on damage in DNA. Examples of modes of action are shown for these inhibitors of induced mutations and implications for reducing genetic damage in man are discussed.