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Nonneural microtubule proteins: Structure and function
Author(s) -
Macrae Thomas H.
Publication year - 1987
Publication title -
bioessays
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.175
H-Index - 184
eISSN - 1521-1878
pISSN - 0265-9247
DOI - 10.1002/bies.950060308
Subject(s) - microtubule , tubulin , function (biology) , biology , microtubule nucleation , microbiology and biotechnology , computational biology , biochemistry , cell , centrosome , cell cycle
Analysis of microtubule proteins from several sources has revealed a molecular complexity consistent with the proposed multi‐functional nature of tubulin and microtubule‐associated proteins (MAP). Less certain is the actual range of functions attributable to microtubules and how the variability exhibited by the microtubule proteins translates into functional specificity. In spite of the conceptual difficulties, an exciting picture of structure/function integration is emerging from the study of microtubules.