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Retrovirus vectors and their uses in molecular biology
Author(s) -
Gilboa Eli
Publication year - 1986
Publication title -
bioessays
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.175
H-Index - 184
eISSN - 1521-1878
pISSN - 0265-9247
DOI - 10.1002/bies.950050605
Subject(s) - retrovirus , biology , gene , gene transfer , vector (molecular biology) , computational biology , mechanism (biology) , genetics , microbiology and biotechnology , recombinant dna , philosophy , epistemology
Retroviral vectors utilize the biochemical processes unique to retroviruses, to transfer genes with high efficiency into a wide variety of cell types in tissue culture and in living animals. With such vectors, the effect of newly introduced genes and the mechanism of gene expression can be studied in cell types so far refractory to other methods of transfer.