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Testicular leydig cells: Differentiated cells responding to multiple hormonal control and producing varied products
Author(s) -
Melner Michael H.
Publication year - 1986
Publication title -
bioessays
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.175
H-Index - 184
eISSN - 1521-1878
pISSN - 0265-9247
DOI - 10.1002/bies.950050511
Subject(s) - paracrine signalling , leydig cell , autocrine signalling , spermatogenesis , hormone , microbiology and biotechnology , biology , function (biology) , endocrinology , medicine , luteinizing hormone , cell culture , biochemistry , receptor , genetics
Leydig cells, traditionally known as the steroidogenic workhorses of the testis, are now known to synthesize significant amounts of non‐steroid products including some potent bioactive proteins and peptides. These products are currently being investigated for their potential role in the paracrine regulation of spermatogenesis in the nearby seminiferous tubules and in the autocrine regulation of Leydig cell function.