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Interstrand duplexes in nuclear RNA
Author(s) -
Pogo A. Oscar,
Miller Kenton S.
Publication year - 1986
Publication title -
bioessays
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.175
H-Index - 184
eISSN - 1521-1878
pISSN - 0265-9247
DOI - 10.1002/bies.950050406
Subject(s) - rna , molecule , nucleus , intermolecular force , chemistry , cell nucleus , biophysics , microbiology and biotechnology , biology , computational biology , biochemistry , gene , organic chemistry
Nuclear intermolecular duplexes appear to be a general feature of nucleated cells. Most of these duplexes are formed between large RNA as well as between large and small RNA molecules. A significant portion of the large molecules belong to a special class of RNA that is restricted to the nucleus and, therefore, not designated for export. These molecules are assembled with proteins and form a structure of a higher order. The possibility that these molecules and a set of small nuclear RNAs are components of a complex machine, “the transportosome”, which functions in nucleocytoplasmic traffic, is discussed.