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Replication origins in yeast chromosomes
Author(s) -
Kearsey Stephen
Publication year - 1986
Publication title -
bioessays
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.175
H-Index - 184
eISSN - 1521-1878
pISSN - 0265-9247
DOI - 10.1002/bies.950040405
Subject(s) - biology , dna replication , control of chromosome duplication , origin of replication , genetics , eukaryotic dna replication , licensing factor , yeast , origin recognition complex , genome , replication (statistics) , dna re replication , pre replication complex , model organism , identification (biology) , dna , computational biology , gene , virology , botany
DNA replication initiates at many sites in eukaryotic chromosomes. It has been difficult to isolate such replication origins, but a family of sequences from the yeast genome have properties which suggest that they may serve this function. The identification of these sequences together with sophisticated methods of genetic analysis, make yeast a useful organism for the study of eukaryotic DNA replication.