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Cell interactions in the developing leech embryo
Author(s) -
Bissen Shirley T.,
Ho Robert K.,
Weisblat David A.
Publication year - 1986
Publication title -
bioessays
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.175
H-Index - 184
eISSN - 1521-1878
pISSN - 0265-9247
DOI - 10.1002/bies.950040404
Subject(s) - leech , cell fate determination , biology , embryo , multicellular organism , hirudo medicinalis , microbiology and biotechnology , embryonic stem cell , cell division , cell , embryogenesis , evolutionary biology , genetics , computer science , world wide web , transcription factor , gene
The stereotyped pattern of cell commitments during leech embryogenesis is described. The nature of cell commitments during segmentation differs significantly between leech and fruit fly. Despite the constancy of cell fate assignments in normal development, ablation experiments show that cell interactions are essential in setting some of these commitments. Interacting cells follow a positionally determined hierarchy of fate choices. For other cells, which appear to have fates fixed from birth, the possibility of determinative interactions between mother and daughter cells is discussed.