Premium
What the papers say: Short odds for malaria vaccines
Author(s) -
Mitchell G. F.
Publication year - 1985
Publication title -
bioessays
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.175
H-Index - 184
eISSN - 1521-1878
pISSN - 0265-9247
DOI - 10.1002/bies.950030309
Subject(s) - plasmodium falciparum , malaria , biology , monoclonal antibody , cloning (programming) , antigen , epitope , virology , gene , immunochemistry , antibody , immunology , genetics , computer science , programming language
The immunology of falciparum malaria, the lethal type of human malaria, has been transformed by two developments. First, a culture system for the asexual blood stages of Plasmodium falciparum. 1 Secondly, the cloning and expression of genes coding for a large number of the protein antigens of this malaria parasite over the past two years. Data on proteins, protein antigens and epitopes of P. falciparum supplied by gene cloning techniques have been supplemented by monoclonal antibody approaches, peptide synthesis, and high‐resolution immunochemistry.