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The role of growth factors in haemopoiesis
Author(s) -
Dexter T. M.,
Heyworth C.,
Whetton A. D.
Publication year - 1985
Publication title -
bioessays
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.175
H-Index - 184
eISSN - 1521-1878
pISSN - 0265-9247
DOI - 10.1002/bies.950020404
Subject(s) - haematopoiesis , biology , microbiology and biotechnology , mode of action , cell growth , growth factor , stem cell , immunology , genetics , biochemistry , receptor
Many of the haemopoietic cell growth factors have now been purified to homogeneity and their structural genes cloned. Methods are also now available for obtaining pure populations of haemopoietic cells. The use of such cells, in combination with pure growth factors, has provided intriguing information about the biological activities and mode of action of the factors in faciliating survival, proliferation and differentiation of the haemopoietic cells.