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Roots: Molecular basis of gene expression: Origins from the Pajama experiment
Author(s) -
Pardee Arthur B.
Publication year - 1985
Publication title -
bioessays
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.175
H-Index - 184
eISSN - 1521-1878
pISSN - 0265-9247
DOI - 10.1002/bies.950020213
Subject(s) - biology , gene , gene expression , operon , regulation of gene expression , repressor , genetics , expression (computer science) , messenger rna , computational biology , regulator gene , evolutionary biology , computer science , escherichia coli , programming language
The Pajama (Pardee, Jacob, Monod) experiment provided a breakthrough in our understanding of the molecular mechanisms by which gene expression is regulated. Today, twenty‐five years later it provides a paradigm for thinking about problems of gene expression, such as growth regulation and differentiation. From this experiment emerged entities such as repressors, regulatory genes, the operon as a group of jointly controlled genes, and messenger RNA.