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The role of E. coli single‐stranded DNA binding protein in DNA metabolism
Author(s) -
Chase John W.
Publication year - 1984
Publication title -
bioessays
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.175
H-Index - 184
eISSN - 1521-1878
pISSN - 0265-9247
DOI - 10.1002/bies.950010509
Subject(s) - dna , escherichia coli , single stranded binding protein , biology , dna binding protein , function (biology) , mechanism (biology) , biochemistry , genetics , gene , transcription factor , philosophy , epistemology
Single‐stranded DNA binding proteins have been known for some time to be crucial in many DNA metabolic reactions in both prokaryotes and eukaryotes. Despite a wealth of studies on these proteins we still do not understand their biochemical mechanism of action. Recent studies of the Escherichia coli single stranded DNA binding protein (SSB) are beginning to provide some insight into how this and similar proteins might function.