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Molecular biology of plasminogen activators and recombinant DNA progress
Author(s) -
CederholmWilliams S. A.
Publication year - 1984
Publication title -
bioessays
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.175
H-Index - 184
eISSN - 1521-1878
pISSN - 0265-9247
DOI - 10.1002/bies.950010408
Subject(s) - recombinant dna , biology , dna , computational biology , enzyme , microbiology and biotechnology , biochemistry , gene
Plasminogen activators are enzymes with multiple roles. They play vital parts in maintaining the functional integrity of the vascular system and they are also involved in processes of tissue reorganization. In this review, the molecular properties of these enzymes that make them ideal targets for genetic and biochemical engineering to satisfy a potential therapeutic role are described.