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The influence of alcohol on female germ cells
Author(s) -
Kaufman M. H.
Publication year - 1984
Publication title -
bioessays
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.175
H-Index - 184
eISSN - 1521-1878
pISSN - 0265-9247
DOI - 10.1002/bies.950010307
Subject(s) - oocyte , embryo , meiosis , mode of action , biology , ethanol , andrology , microbiology and biotechnology , genetics , alcohol , chromosome , toxicology , biochemistry , gene , medicine
The teratogenic effect of ethanol on human and animal embryos is now well documented. Recent studies have clearly demonstrated that ethanol and related spindle‐acting agents may additionally interfere with normal meiotic chromosome segregation during oocyte maturation, leading to the production of aneuploid embryos. The mode of action, and potential hazard posed by these agents is considered.