Premium
What the papers say: A molecular theme for homoeotic genes
Author(s) -
Akam Michael
Publication year - 1984
Publication title -
bioessays
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.175
H-Index - 184
eISSN - 1521-1878
pISSN - 0265-9247
DOI - 10.1002/bies.950010210
Subject(s) - gene , biology , genetics , computational biology , coding region , conserved sequence , evolutionary biology , base sequence
Homoeotic mutations alter the pattern of development by causing one body part to develop as some other. Among the genes identified by homoeotic mutations in Drosophila are some whose products appear to control development. A number of these have now been shown to share a common protein coding domain, which carries a sequence motif characteristic of DNA binding proteins. This protein coding domain is highly conserved in a wide range of animal taxa, including vertebrates.