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BioEssays 6∕2017
Publication year - 2017
Publication title -
bioessays
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.175
H-Index - 184
eISSN - 1521-1878
pISSN - 0265-9247
DOI - 10.1002/bies.201770061
Subject(s) - sumo protein , chromatin , function (biology) , biology , citation , genetics , rna polymerase ii , computational biology , microbiology and biotechnology , ubiquitin , dna , computer science , library science , promoter , gene , gene expression
Chromatin SUMO in stress . In article 1600263 , Einari A. Niskanen and Jorma J. Palvimo ponder the role of chromatin SUMOylation in cell stress. Post‐translational modification of chromatin proteins with SUMOs, small ubiquitin‐like modifier proteins, responds to various harsh stress conditions. However, the function of this SUMO stress response is not known. The cover schematizes their hypothesis that as reactions to cell stress, decreased SUMOylation of chromatin anchor regions and increased SUMOylation in promoter regions regulate chromatin structural changes and RNA polymerase II pausing, respectively.