Is anti‐viral defence the evolutionary origin of mRNA turnover? (Comment on DOI  10.1002/bies.201600100 ) | Zendy

Rehwinkel Jan | Zendy

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Is anti‐viral defence the evolutionary origin of mRNA turnover? (Comment on DOI 10.1002/bies.201600100 )

Author(s) -

Rehwinkel Jan

Publication year - 2016

Publication title -

bioessays

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.175

H-Index - 184

eISSN - 1521-1878

pISSN - 0265-9247

DOI - 10.1002/bies.201600140

Subject(s) - biology , messenger rna , nonsense mediated decay , translation (biology) , rna , gene , genetics , microbiology and biotechnology , p bodies , gene expression , rna splicing

"Is anti-viral defence the evolutionary origin of mRNA turnover?": Comment by J Rehwinkel on "Exaptive origins of regulated mRNA decay in eukaryotes" Hamid and Makeyev (2016; 10.1002/bies.201600100). In this issue of BioEssays, Hamid and Makeyev explore an interesting new idea regarding the evolutionary origins of regulated mRNA turnover pathways ... This hypothesis – that molecular mechanisms nowadays primarily involved in regulated mRNA decay have their origin in anti-viral defence – provides interesting new perspectives on host-pathogen co-evolution and on molecular recognition of RNA

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