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BioEssays 3∕2015
Publication year - 2015
Publication title -
bioessays
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.175
H-Index - 184
eISSN - 1521-1878
pISSN - 0265-9247
DOI - 10.1002/bies.201470031
Subject(s) - anaphase , telophase , cyan , punctuation , transition (genetics) , biology , chromosome , computer science , genetics , physics , artificial intelligence , gene , optics
A chromosome separation checkpoint. On pages 257–266, Maiato et al. discuss a “chromosome separation checkpoint” that regulates the anaphasetelophase transition. The cover depicts an LLC‐PK cell at the anaphase‐telophase transition. This transition is spatially regulated by a spindle midzone Aurora B activity gradient (light pink) revealed by the gradual dephosphorylation of Histone H3 on Ser10 (green) as chromosomes (magenta) migrate towards the poles where nuclear envelope (cyan blue) reformation begins. Microtubules are shown in white and actin filaments also in cyan blue define the cell borders. Interphase nuclei are shown in violet. Photo credits: Helder Maiato and Olga Afonso.