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Organelle size control systems: From cell geometry to organelle‐directed medicine
Author(s) -
Marshall Wallace F.
Publication year - 2012
Publication title -
bioessays
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.175
H-Index - 184
eISSN - 1521-1878
pISSN - 0265-9247
DOI - 10.1002/bies.201200043
Subject(s) - organelle , microbiology and biotechnology , cell , organelle biogenesis , control (management) , biology , computational biology , chemistry , computer science , biochemistry , artificial intelligence , biogenesis , gene
Organelles are reaction vessels containing metabolic pathways. As in a chemical factory, the size of the reaction vessels limits the rate of product formation. Organelle size is tuned to metabolic needs, hence reprogramming organelle size could be a novel therapeutic strategy as well as a new tool for metabolic engineering.