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Biomarker development: Prudence, risk, and reproducibility
Author(s) -
Dougherty Edward R.
Publication year - 2012
Publication title -
bioessays
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.175
H-Index - 184
eISSN - 1521-1878
pISSN - 0265-9247
DOI - 10.1002/bies.201200003
Subject(s) - prudence , biomarker , reproducibility , medicine , biology , chemistry , chromatography , genetics , philosophy , theology
Is a two‐fold approach — preliminary studies based on small samples followed by a large‐sample study to check reproducibility — in the search for biomarkers really prudent?
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