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Basophils: Important emerging players in allergic and anti‐parasite responses
Author(s) -
Schwartz Christian,
Voehringer David
Publication year - 2011
Publication title -
bioessays
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.175
H-Index - 184
eISSN - 1521-1878
pISSN - 0265-9247
DOI - 10.1002/bies.201100028
Subject(s) - immune system , immunology , allergic inflammation , biology , inflammation , transgene , antigen , parasite hosting , genetically modified mouse , microbiology and biotechnology , genetics , gene , world wide web , computer science
The recent development of transgenic mouse strains depleted in basophils has helped in elucidating the diverse functions of basophils in the primary in secondary immune responses: from acting as antigen‐presenting cells and contributing to B cell activation to their role in allergic inflammation, worm expulsion and tick resistance.