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BioEssays 6/2010
Author(s) -
Kim ManSun,
Kim JeongRae,
Cho KwangHyun
Publication year - 2010
Publication title -
bioessays
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.175
H-Index - 184
eISSN - 1521-1878
pISSN - 0265-9247
DOI - 10.1002/bies.201090019
Subject(s) - drosophila melanogaster , biology , drosophila (subgenus) , identification (biology) , evolutionary biology , gene regulatory network , development (topology) , constellation , cover (algebra) , computational biology , computer science , genetics , gene , mathematics , physics , gene expression , ecology , mechanical engineering , mathematical analysis , engineering , astronomy
Cover Photograph: Resolving developmental genetics in the fourth dimension: an illustration (by Kwang‐Hyun Cho himself) of the principle of dynamic network motifs in Drosophila development. Hitherto largely considered in terms of time‐invariant networks, drosophila development is viewed in the article by Man‐Sun Kim, Jeong‐Rae Kim, and Kwang‐Hyun Cho as the result of networks of gene interactions that change during the course of development. Using this paradigm, pivotal developmental events can be correlated with particular changes from one constellation of gene interactions to a different one, and the method allows the identification of certain network motifs that are not identifiable using static approaches. Features article: “Dynamic network rewiring determines temporal regulatory functions in the Drosophila melanogaster development processes”, see pages 505 – 513 .