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Biologic effects of prolonged exposure to ELF electromagnetic fields in rats: II. 50 Hz magnetic fields
Author(s) -
Margonato V.,
Nicolini P.,
Conti R.,
Zecca L.,
Veicsteinas A.,
Cerretelli P.
Publication year - 1995
Publication title -
bioelectromagnetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.435
H-Index - 81
eISSN - 1521-186X
pISSN - 0197-8462
DOI - 10.1002/bem.2250160602
Subject(s) - hematology , histology , bone marrow , medicine , lymph , endocrinology , physiology , pathology , biology
To provide possible laboratory support to health risk evaluation associated with long‐term, low‐intensity magnetic field exposure, 256 male albino rats and an equal number of control animals (initial age 12 weeks) were exposed 22 h/day to a 50 Hz magnetic flux density of 5 μmT for 32 weeks (a total of about 5000 h). Hematology was studied from blood samples before exposure to the field and at 12 week intervals. Morphology and histology of liver, heart, mesenteric lymph nodes, and testes as well as brain neurotransmitters were assessed at the end of the exposure period. In two identical sets of experiments, no significant differences in the investigated variables were found between exposed and sham‐exposed animals. It is concluded that continuous exposure to a 50 Hz magnetic field of 5 μT from week 12 to week 44, which makes up ˜70% of the life span of the rat before sacrifice, does not cause changes in growth rate, in the morphology and histology of liver, heart, mesenteric lymph nodes, testes, and bone marrow, in hematology and hematochemistry, or in the neurotransmitters dopamine and serotonin. © 1995 Wiley‐Liss, Inc.