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Effects of static magnetic field on specific adenosine‐5′‐triphosphatase activities and bioelectrical and biomechanical properties in the rat diaphragm muscle
Author(s) -
Iteǧgin Mustafa,
Günay Ismail,
Loǧoǧlu Gülay,
Isbir Turgay
Publication year - 1995
Publication title -
bioelectromagnetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.435
H-Index - 81
eISSN - 1521-186X
pISSN - 0197-8462
DOI - 10.1002/bem.2250160302
Subject(s) - atpase , diaphragm (acoustics) , bioelectromagnetics , chemistry , magnetic field , biophysics , anatomy , medicine , nuclear magnetic resonance , endocrinology , biology , biochemistry , enzyme , physics , quantum mechanics , acoustics , loudspeaker
In this study, we aimed to clarify the effects of chronically applied static magnetic field (200 Gauss) on specific ATPase activities and bioelectrical and biomechanical responses in the isolated rat diaphragm muscle. The mean activities of Na + ‐K + ATPase and Ca 2+ ATPase determined from the diaphragm homogenates were significantly higher in the magnetic field exposed group (n = 20), but that of Mg 2+ ATPase was nonsignificantly lower compared to the control group (n = 13). Resting membrane potential, amplitude of muscle action potential, and overshoot values (mean ± SE) in the control group were found to be −76.5 ± 0.6, 100 ± 0.8, and 23.5 ± 0.6 mV, respectively; these values were determined to be −72.8 ± 0.4, 90.3 ± 0.5, and 17.2 ± 0.4 mV in the magnetic field‐exposed group, respectively. The latency was determined to increase in the experimental group, and all the above‐mentioned bioelectrical differences between the groups were significant statistically. Force of muscle twitch was found to decrease significantly in the magnetic field‐exposed group, and this finding was attributed to the augmenting effect of magnetic field on Ca 2+ ATPase activity. These results suggest that magnetic field exposure changes specific ATPase activities and, thence, bioelectrical and biomechanical properties in the rat diaphragm muscle. © 1995 Wiley‐Liss, Inc.