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Imprecise exposure assessment and the sample size requirements of case‐control studies of residential magnetic field exposure and cancer in adults
Author(s) -
Delpizzo Vincent
Publication year - 1995
Publication title -
bioelectromagnetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.435
H-Index - 81
eISSN - 1521-186X
pISSN - 0197-8462
DOI - 10.1002/bem.2250160210
Subject(s) - sample size determination , exposure assessment , control (management) , sample (material) , neglect , statistics , environmental health , computer science , environmental science , reliability engineering , toxicology , mathematics , medicine , engineering , chemistry , artificial intelligence , nursing , chromatography , biology
A computer program simulating case‐control studies is described. It is used to estimate the minimum sample size required and to assess how this is affected by imprecise exposure assessment. In particular, the consequences of neglecting measurements of nonresidential exposure in case‐control studies of residentially exposed adults are investigated. According to this model, while the consequent loss of power is not as large as was predicted by algebraic methods, it would be unwise to neglect it when planning a study. © 1995 Wiley‐Liss, Inc.