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Effects of extremely‐law‐frequency electromagnetic fields on ion transport in several mammalian cells
Author(s) -
GarcíaSancho Javier,
Montero Mayte,
Alvarez Javier,
Fonteriz Rosalba I.,
Sanchez Ana
Publication year - 1994
Publication title -
bioelectromagnetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.435
H-Index - 81
eISSN - 1521-186X
pISSN - 0197-8462
DOI - 10.1002/bem.2250150611
Subject(s) - extremely low frequency , hl60 , biophysics , cytosol , intracellular , ion , ion transporter , chemistry , nuclear magnetic resonance , electromagnetic field , cell , biology , biochemistry , physics , organic chemistry , quantum mechanics , enzyme
We have investigated the effects of sinusoidal electromagnetic fields (EMF) on ion transport (Ca 2+ , Na + , K + , and H + ) in several cell types (red blood cells, thymocytes, Ehrlich ascites tumor cells, and HL60 and U937 human leukemia cells). The effects on the uptake of radioactive tracers as well as on the cytosolic Ca 2+ concentration ([Ca 2+ ] i ), the intracellular pH (pH i ), and the transmembrane potentsial (TMP) were studied. Exposure to EMF at 50 Hz and 100–2000 μT (rms) had no significant effects on any of these parameters. Exposure to EMF of 20–1200 μT (rms) at the estimated cyclotron magnetic resonance frequencies for the respective ions had no significant effects except for a 12–32% increase of the uptake of 42 K within a window at 14.5–15.5 Hz and 100–200 μT (rms), which was found in U937 and Ehrlich cells but not in the other cell types. © 1994 Wiley‐Liss, Inc.