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Influence of microwaves on the beating rate of isolated rat hearts
Author(s) -
Yee KuoChiang,
Chou ChungKwang,
Guy Arthur W.
Publication year - 1988
Publication title -
bioelectromagnetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.435
H-Index - 81
eISSN - 1521-186X
pISSN - 0197-8462
DOI - 10.1002/bem.2250090209
Subject(s) - heart rate , beat (acoustics) , cardiology , perfusion , heart beat , medicine , microwave , materials science , physics , blood pressure , optics , quantum mechanics
Previous reports have shown that microwave exposure can decrease the beating rate of isolated rat hearts. These experiments were conducted at room temperature and with the hearts exposed to air. We observed arrhythmia frequently at room temperature, and the variation of heart beat was so large that it makes the results difficult to reproduce. Therefore, we employed a double‐circulating system to provide perfusion through the coronary artery and around the outside of the heart to maintain the rat hearts at 37.7°C. No arrhythmias were observed in our experiments, and the hearts were beating for at least 1 h. The effects of 16‐Hz modulated 2,450‐MHz pulsed microwaves (10 μs, 100 pps) on the beating rate of 50 isolated rat hearts were studied. Results showed no statistically significant changes of heart rate in exposed groups at SARs of 2 and 10 W/kg compared with the control group. The effect seen at 200 W/kg was shown to be similar to that resulting from heating the heart.