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Development of young rats and rabbits exposed to a strong electric field
Author(s) -
Portet R.,
Cabanes J.
Publication year - 1988
Publication title -
bioelectromagnetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.435
H-Index - 81
eISSN - 1521-186X
pISSN - 0197-8462
DOI - 10.1002/bem.2250090109
Subject(s) - medicine , endocrinology , corticosterone , hormone , epinephrine , thyroid , norepinephrine , gestation , biology , pregnancy , dopamine , genetics
Body growth and circulating levels of hormones were assessed in young rats and rabbits exposed to a 50‐Hz electric field of 50 kV/m. Eight‐week‐old male rats were exposed 8 h/ day for 4 weeks and rabbits were exposed 16 h/day from the last 2 weeks of gestation to 6 weeks after birth. The body and the organ growth of exposed rats were not statistically different from those of sham‐exposed controls. No important differences from controls were observed in plasma levels of corticosterone, TSH, ACTH, and T 4 or in adrenal levels of epinephrine, norepinephrine, and corticosterone although T 3 was slightly, but significantly, decreased. No large histological changes in the thyroid or adrenals were noted. In rabbits, organ and body wieghts of exposed animals were comparable to those of controls. Plasma levels of various hormones (ACTH, GH, T 3 , T 4 , corticosterone, cortisol), serum glucose, triglycerides, and cholesterol were not significantly altered. Adrenal content of cortisol was lower, however, in exposed rabbits. No histological changes of the thyroid or adrenal glands were observed.