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Effects of ELF (1–120 Hz) and modulated (50 Hz) RF fields on the efflux of calcium ions from brain tissue in vitro
Author(s) -
Blackman C. F.,
Benane S. G.,
House D. E.,
Joines W. T.
Publication year - 1985
Publication title -
bioelectromagnetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.435
H-Index - 81
eISSN - 1521-186X
pISSN - 0197-8462
DOI - 10.1002/bem.2250060102
Subject(s) - efflux , ion , calcium , in vitro , amplitude , biophysics , electromagnetic field , intensity (physics) , nuclear magnetic resonance , chemistry , physics , biology , optics , biochemistry , quantum mechanics , organic chemistry
We have previously shown that 16‐Hz, sinusoidal electromagnetic fields can cause enhanced efflux of calcium ions from chick brain tissue, in vitro, in two intensity regions centered on 6 and 40 V p‐p /m. Alternatively, 1‐Hz and 30‐Hz fields at 40 V p‐p /m did not cause enhanced efflux. We now demonstrate that although there is no enhanced efflux associated with a 42‐Hz field at 30, 40, 50, or 60 V p‐p /m, a 45‐Hz field causes enhanced efflux in an intensity range around 40 V p‐p /m that is essentially identical to the response observed for 16‐Hz fields. Fields at 50 Hz induce enhanced efflux in a narrower intensity region between 45 and 50 V p‐p /m, while radiofrequency carrier waves, amplitude modulated at 50 Hz, also display enhanced efflux over a narrow power density range. Electromagnetic fields at 60 Hz cause enhanced efflux only at 35 and 40 V p‐p /m, intensities slightly lower than those that are effective at 50 Hz. Finally, exposures over a series of frequencies at 42.5 V p‐p /m reveal two frequency regions that elicit enhanced efflux—one centered on 15 Hz, the other extending from 45 to 105 Hz.