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Magnetic field effects on calcium efflux and insulin secretion in isolated rabbit islets of Langerhans
Author(s) -
Jolley Weldon B.,
Hinshaw Daniel B.,
Knierim Kathleen,
Hinshaw David B.
Publication year - 1983
Publication title -
bioelectromagnetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.435
H-Index - 81
eISSN - 1521-186X
pISSN - 0197-8462
DOI - 10.1002/bem.2250040110
Subject(s) - endocrinology , medicine , insulin , stimulation , islet , efflux , calcium , rabbit (cipher) , chemistry , biology , biochemistry , statistics , mathematics
Abstract Rabbit islets of Langerhans were exposed at 37 °C for 18 h to a low‐frequency‐pulsed magnetic field, generated in paired Helmholtz coils. Exposed islets showed a reduction of 26.1 ± 4.3% in 45 Ca 2+ content (P < .004). a reduction of 25.1 ± 6.3% in 45 Ca 2+ efflux (P < .006), and a reduction of 35.0 ± 8.7% (P < .002) in insulin released during glucose stimulation when compared with appropriate controls.