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Lack of effect of 2.45‐GHz microwave radiation on the development of preimplantation embryos of mice
Author(s) -
Inouye Minoru,
Galvin Michael J.,
McRee Donald I.,
Matsumoto Nobuo
Publication year - 1982
Publication title -
bioelectromagnetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.435
H-Index - 81
eISSN - 1521-186X
pISSN - 0197-8462
DOI - 10.1002/bem.2250030211
Subject(s) - embryo , microwave , biology , andrology , microbiology and biotechnology , medicine , engineering , telecommunications
The development of preimplantation embryos after exposure to microwave radiation was studied. Female CD‐1 mice were induced to superovulate, mated, and exposed to 2.45‐GHz microwave or sham radiation for 3 h at power densities of 9 mW/cm 2 and 19 mW/cm 2 on either day 2 or 3 of pregnancy (plug day was considered day 1). Another group of mice was exposed to heat stress by placing the dams in an environmental room at an ambient temperature of 38 °C and relative humidity at 62% for 3 h on day 2 of pregnancy. All groups were euthanized on day 4 of pregnancy and embryos were recovered by flushing excised uterine horns. Embryos were examined for abnormalities and classified by the developmental stages. They were then treated with hypotonic solution and dissociated for counting blastomeres. Heat stress caused stunted development of embryos, but no remarkable effect of microwave radiation could be found on the development of preimplantation embryos.