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Active electric properties of cardiac muscle
Author(s) -
Geselowitz David B.,
Miller W. T.
Publication year - 1982
Publication title -
bioelectromagnetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.435
H-Index - 81
eISSN - 1521-186X
pISSN - 0197-8462
DOI - 10.1002/bem.2250030116
Subject(s) - extracellular , bidomain model , intracellular , syncytium , transmembrane protein , cardiac muscle , cable theory , biophysics , electrical current , electrical resistivity and conductivity , physics , chemistry , biology , neuroscience , microbiology and biotechnology , computer science , anatomy , electrical engineering , biochemistry , engineering , cell , telecommunications , receptor , quantum mechanics , cable gland , cable harness
A model of electrical activity in the heart has been developed that treats the intracellular domain and the extracellular domain as electrical syncytia with anisotropic resistivities (bi‐syncytial model). At the microscopic level, propagation is assumed to proceed primarily along the axes of individual cells. Considerations at the macroscopic level relate the transmembrane current to the intracellular and extracellular resistivity and the transmembrane potential. The result is a relationship between instantaneous extracellular potentials and cardiac action potentials.