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Variation in dielectric properties due to pathological changes in human liver
Author(s) -
Peyman Azadeh,
Kos Bor,
Djokić Mihajlo,
Trotovšek Blaž,
LimbaeckStokin Clara,
Serša Gregor,
Miklavčič Damijan
Publication year - 2015
Publication title -
bioelectromagnetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.435
H-Index - 81
eISSN - 1521-186X
pISSN - 0197-8462
DOI - 10.1002/bem.21939
Subject(s) - bioelectromagnetics , electroporation , dielectric , microwave , pathological , materials science , liver tissue , irreversible electroporation , electric field , human liver , biomedical engineering , nuclear magnetic resonance , optoelectronics , computer science , electromagnetic field , pathology , medicine , chemistry , physics , telecommunications , biochemistry , quantum mechanics , gene , enzyme
Dielectric properties of freshly excised human liver tissues (in vitro) with several pathological conditions including cancer were obtained in frequency range 100 MHz–5 GHz. Differences in dielectric behavior of normal and pathological tissues at microwave frequencies are discussed based on histological information for each tissue. Data presented are useful for many medical applications, in particular nanosecond pulsed electroporation techniques. Knowledge of dielectric properties is vital for mathematical calculations of local electric field distribution inside electroporated tissues and can be used to optimize the process of electroporation for treatment planning procedures. Bioelectromagnetics. 36:603–612, 2015. © 2015 Wiley Periodicals, Inc.