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Genotoxicity investigation of ELF‐magnetic fields in Salmonella typhimurium with the sensitive SOS‐based VITOTOX test
Author(s) -
Verschaeve Luc,
Anthonissen Roel,
Grudniewska Magda,
Wudarski Jakub,
Gevaert Lieven,
Maes Annemarie
Publication year - 2011
Publication title -
bioelectromagnetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.435
H-Index - 81
eISSN - 1521-186X
pISSN - 0197-8462
DOI - 10.1002/bem.20672
Subject(s) - genotoxicity , salmonella , bioelectromagnetics , bacteria , microbiology and biotechnology , ames test , chemistry , biology , magnetic field , physics , genetics , toxicity , organic chemistry , quantum mechanics
We performed a genotoxicity investigation of extremely low‐frequency (ELF) magnetic fields (MFs, 50 Hz, 100 and 500 µT, 1 and 2 h exposure) alone and in combination with known chemical mutagens using the VITOTOX test. This test is a very sensitive reporter assay of Salmonella typhimurium bacteria based on the SOS response. Our study showed that ELF‐MFs do not induce SOS‐based mutagenicity in S. typhimurium bacteria and do not show any synergetic effect when combined with chemical mutagens. Bioelectromagnetics 32:580–584, 2011. © 2011 Wiley‐Liss, Inc.