Premium
Optimization of static magnetic field parameters improves analgesic effect in mice
Author(s) -
László János,
Reiczigel Jenő,
Székely László,
Gasparics Antal,
Bogár István,
Bors László,
Rácz Bernadette,
Gyires Klára
Publication year - 2007
Publication title -
bioelectromagnetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.435
H-Index - 81
eISSN - 1521-186X
pISSN - 0197-8462
DOI - 10.1002/bem.20341
Subject(s) - analgesic , bioelectromagnetics , magnet , stimulus (psychology) , addiction , magnetic field , medicine , computer science , anesthesia , physical medicine and rehabilitation , biomedical engineering , physical therapy , neuroscience , physics , psychology , cognitive psychology , mechanical engineering , engineering , quantum mechanics
The present study deals with the analgesic effect induced by static magnetic fields (SMF) in mice exposed to the field with their whole body. It discusses how the effect depends on the distribution of the magnetic field, that is, on the specification and arrangement of the applied individual permanent magnets. A critical analysis of different magnet arrangements is given. As a result the authors propose a magnet arrangement recipe that achieves an analgesic effect of over 80% in the writhing test. This is a widely accepted screening method for animal pain and predictor of human experimental results. As a non‐drug, non‐invasive, non‐contact, non‐pain, non‐addictive method for analgesia with immediate and long‐lasting effect based on the stimulus of the endogenous opioid network, the SMF treatment may attract the attention of medical doctors, nurses, magnet therapists, veterinarians, physiotherapists, masseurs, and fitness trainers among others. Bioelectromagnetics 28:615–627, 2007. © 2007 Wiley‐Liss, Inc.