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Effects on apoptosis and reactive oxygen species formation by Jurkat cells exposed to 50 Hz electromagnetic fields
Author(s) -
Palumbo R.,
Capasso D.,
Brescia F.,
Mita P.,
Sarti M.,
Bersani F.,
Scarfi M.R.
Publication year - 2006
Publication title -
bioelectromagnetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.435
H-Index - 81
eISSN - 1521-186X
pISSN - 0197-8462
DOI - 10.1002/bem.20199
Subject(s) - jurkat cells , reactive oxygen species , apoptosis , bioelectromagnetics , fas receptor , electromagnetic field , chemistry , biophysics , cell culture , microbiology and biotechnology , oxygen , immunology , biology , programmed cell death , biochemistry , physics , genetics , t cell , immune system , organic chemistry , quantum mechanics
The effect of exposure to 50 Hz electromagnetic field on a human T‐leukaemia cell line (Jurkat) was investigated by evaluating the reactive oxygen species (ROS) production and apoptosis, both spontaneous and induced by a specific anti Fas/CD95 monoclonal antibody (anti‐Fas). Our results suggest that 1 h intermittent (5 min field on/10 min field off) exposure does not affect ROS formation, while a slight but statistically significant decrease of both spontaneous and anti‐Fas‐induced apoptosis was observed. Bioelectromagnetics 27:159–162, 2006. © 2005 Wiley‐Liss, Inc.