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Effects of non‐uniform static magnetic fields on the rate of myosin phosphorylation
Author(s) -
Engström Stefan,
Markov Marko S.,
McLean Michael J.,
Holcomb Robert R.,
Markov Julia M.
Publication year - 2002
Publication title -
bioelectromagnetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.435
H-Index - 81
eISSN - 1521-186X
pISSN - 0197-8462
DOI - 10.1002/bem.10035
Subject(s) - magnet , magnetic field , axial symmetry , materials science , perpendicular , range (aeronautics) , optics , amplitude , nuclear magnetic resonance , physics , geometry , composite material , mathematics , quantum mechanics
The effect on myosin phosphorylation from exposure to a magnetic field generated by an array of four permanent magnets was investigated. Two lateral positions in the non‐uniform field over the array were explored, each at four vertical distances over the surface of the device. The rate of myosin phosphorylation was found to depend on the position laterally over the array as well as the distance from the device surface. The square magnet array was comprised of axially magnetized, cylindrical NdFeB permanent magnets arranged with poles of alternating polarity in a plane (MagnaBloc™ therapeutic device). Detailed dosimetry of the magnet array was compiled: the magnetic flux density averaged over the exposure volume spanned the range 0.7–86 mT for the eight different exposure positions. The corresponding range for the absolute field gradient was 0.4–20 T/m. Comparing the dosimetry to the experimental outcome, our results imply that magnetic field amplitude alone is not sufficient to describe the influence of the field in this preparation. Bioelectromagnetics 23:475–479, 2002. © 2002 Wiley‐Liss, Inc.