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One week of exposure to 50 Hz, vertical magnetic field does not reduce urinary 6‐sulphatoxymelatonin excretion of male wistar rats
Author(s) -
Bakos József,
Nagy Noémi,
Thuróczy György,
Szabó László D.
Publication year - 2002
Publication title -
bioelectromagnetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.435
H-Index - 81
eISSN - 1521-186X
pISSN - 0197-8462
DOI - 10.1002/bem.10014
Subject(s) - urine , excretion , nocturnal , melatonin , endocrinology , creatinine , medicine , urinary system , metabolite , circadian rhythm , chemistry
The effect of exposure to 100 or 50 μT, 50 Hz, vertical magnetic field on the excretion of 6‐sulphatoxymelatonin (6SM) in the nocturnal urine of rats was studied. Twelve male Wistar rats were kept under 12:12 hr light:dark conditions. The nocturnal urine of animals was collected in metabolic cages over 4 consecutive weeks. The concentration of 6SM in the rat urine was measured by 125 I radioimmunoassay and normalized to creatinine concentration. After the first week of urine collection, 6 rats were exposed to 100 µT or 50 µT flux density magnetic fields (MF) for 8 hr daily for 1 week. It was found that the excretion of the primary metabolite of melatonin in the urine, 6SM, did not show statistically significant changes during and after magnetic field exposure. Bioelectromagnetics 23:245–248, 2002. © 2002 Wiley‐Liss, Inc.