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Comorbidities in children with intellectual disabilities
Author(s) -
MarkovicJovanovic Snezana R.,
Milovanovic Jelena D.,
Jovanovic Aleksandar N.,
Zivkovic Jovan B.,
Balovic Aleksandra D.,
Nickovic Vanja,
Vasic Maja Z.,
Ristic Milka Z.
Publication year - 2020
Publication title -
birth defects research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.845
H-Index - 17
ISSN - 2472-1727
DOI - 10.1002/bdr2.1587
Subject(s) - intellectual disability , psychomotor learning , pediatrics , medicine , incidence (geometry) , psychomotor retardation , apgar score , congenital malformations , birth weight , psychiatry , pregnancy , pathology , physics , cognition , alternative medicine , biology , optics , genetics
Background Intellectual disability (ID) is registered in 2%–3% of newborns. In most cases, the causes are not identifiable. Objective We explored the correlation between the intellectual disability and gestational age, birth weight, Apgar score, familial diseases, congenital anomalies, and acquired medical disorders, with the aim to estimate the prevalence and severity of comorbidities in the affected children. Methods Our study included 22 children with ID, and 24 with proper psychomotor development, aged 5–10 who were not considered to have ID. Results The presence of familial disorders and CNS congenital anomalies increased the risk of ID 4.147 and 2.59 times, respectively. The risk for other congenital and noncongenital diseases was higher (7.38 and 1.4 times, respectively) in children with intellectual disability. Conclusions Children with intellectual disabilities have higher incidence of congenital diseases, family disorders and a higher frequency of acquired disorders during childhood. Apgar score is a sensitive predictor of morbidity regarding congenital as well as noncongenital medical conditions.